CBD
“Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action“ by Roger Pertwee (2012) – This comprehensive review paper discusses the pharmacological properties and potential therapeutic applications of CBD, highlighting its diverse effects on various physiological systems.
“Cannabidiol as a Potential Treatment for Anxiety Disorders“ by Esther M. Blessing, Maria M. Steenkamp, Jorge Manzanares, and Charles R. Marmar (2015) – This review article summarizes preclinical and clinical evidence supporting the anxiolytic effects of CBD, suggesting its potential as a novel treatment for anxiety disorders.
“Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders“ by Orrin Devinsky, Maria Roberta Cilio, Helen Cross, Javier Fernandez-Ruiz, Jacqueline French, Charlotte Hill, Russell Katz, Vincenzo Di Marzo, Didier Jutras-Aswad, William George Notcutt, Jose Martinez-Orgado, Philip J. Robson, Brian G. Rohrback, Elizabeth Thiele, Benjamin Whalley, and Daniel Friedman (2014) – This article provides a comprehensive overview of the pharmacology of CBD and its potential therapeutic applications, with a focus on epilepsy and other neuropsychiatric disorders.
Ketamine
Ketamine Therapy for PTSD and Treatment-Resistant Depression: Discover the Benefits & Process
“Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression“ by Carlos A. Zarate Jr., Jaskaran B. Singh, Paul J. Carlson, Nancy E. Brutsche, Rezvan Ameli, David A. Luckenbaugh, Raul R. Charney, and Dennis S. Charney (2006) – This study is often cited for its pioneering work in demonstrating the rapid antidepressant effects of ketamine in patients with treatment-resistant depression.
“A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression“ by Aan Het Rot M, Collins KA, Murrough JW, Perez AM, Reich DL, Charney DS, Mathew SJ (2010) – This double-blind, placebo-controlled trial investigated the antidepressant effects of ketamine in patients with treatment-resistant major depression, providing further evidence for its rapid onset of action.
“Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics“ by Carlos A. Zarate Jr., and Husseini K. Manji (2008) – This review article provides a comprehensive overview of the emerging role of ketamine and other rapid-acting antidepressants in the treatment of mood disorders. It discusses the neurobiological mechanisms underlying the rapid antidepressant effects of ketamine and explores its potential implications for the development of novel therapeutics.
Psilocybin
“Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial“ by Griffiths, R. R., Johnson, M. W., et al. (2016) – This randomized double-blind trial investigated the therapeutic potential of psilocybin in reducing depression and anxiety in patients with life-threatening cancer. The study demonstrated significant and sustained decreases in symptoms following psilocybin-assisted psychotherapy.
“Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial“ by Ross, S., Bossis, A., et al. (2016) – This randomized controlled trial examined the efficacy of psilocybin-assisted therapy in reducing symptoms of anxiety and depression in patients with life-threatening cancer. It found rapid and sustained symptom reduction following psilocybin treatment.
“Psilocybin-occasioned mystical-type experience in combination with meditation and other spiritual practices produces enduring positive changes in psychological functioning and in trait measures of prosocial attitudes and behaviors“ by Griffiths, R. R., et al. (2018) – This study explored the combination of psilocybin with meditation and other spiritual practices and its effects on psychological functioning and prosocial attitudes. It found enduring positive changes in these domains.