“Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression“ by Carlos A. Zarate Jr., Jaskaran B. Singh, Paul J. Carlson, Nancy E. Brutsche, Rezvan Ameli, David A. Luckenbaugh, Raul R. Charney, and Dennis S. Charney (2006) – This study is often cited for its pioneering work in demonstrating the rapid antidepressant effects of ketamine in patients with treatment-resistant depression.
“A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression“ by Aan Het Rot M, Collins KA, Murrough JW, Perez AM, Reich DL, Charney DS, Mathew SJ (2010) – This double-blind, placebo-controlled trial investigated the antidepressant effects of ketamine in patients with treatment-resistant major depression, providing further evidence for its rapid onset of action.
“Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics“ by Carlos A. Zarate Jr., and Husseini K. Manji (2008) – This review article provides a comprehensive overview of the emerging role of ketamine and other rapid-acting antidepressants in the treatment of mood disorders. It discusses the neurobiological mechanisms underlying the rapid antidepressant effects of ketamine and explores its potential implications for the development of novel therapeutics.